Cancer

Surgical considerations in invasive breast cancer: A clinician's update

, Amy J. Goldberg, MD, FACS May 10, 2012

Breast cancer requires a multidisciplinary approach in which all clinicians should have a fundamental knowledge of the armamentarium of other team members.
 

An aggressive necrotic skin lesion

, Christopher P. Forest, MSHS, PA-C April 18, 2012

A chemical burn suffered more than 3 decades ago is the underlying cause of a multinodular mass with central erythema.
 

Tuberculosis screening: Prevention in the patient with immunosuppression

, April 10, 2012

Identifying patients with latent TB is paramount because reactivation is possible any time the immune system becomes depressed.
 

Hereditary breast and ovarian cancer

, March 26, 2012

Patients who test positive for the BRCA1/2 mutations that cause breast and ovarian cancers have options when it comes to surveillance and prevention.
 

A facial lesion concerns an at-risk patient

March 08, 2012

The lesion was asymptomatic, but the patient's history raised her own index of suspicion, not just the clinician's.
 

Evaluating a neck mass: Narrowing the differential diagnosis

, Ryan Marovich, MPAS, PA-C; Jonas T. Johnson, MD, FACS March 01, 2012

The differential diagnosis of a neck mass can be overwhelming, even for an experienced clinician. A thorough knowledge of head and neck anatomy is most helpful.
 

C-reactive protein: A clinically useful biomarker in renal cell carcinoma

, Jennifer DeLong, PA; Viraj A. Master, MD, PhD January 16, 2012

Biochemical markers of inflammation, specifically CRP, serve as adjuncts to TNM staging 
to help identify patients at increased risk for recurrence of kidney cancer.
 

What's new in lung cancer: 
Screening, staging, targeted therapies

December 09, 2011

Chemotherapy damages both normal cells and tumor cells, but newer agents target specific biomarkers to inhibit cancer growth and progression.
 

How is this web space lesion best treated?

November 09, 2011

Deciding the best approach to a hard-to-monitor lesion of unknown duration required judgment based on both objective and subjective input.
 

Intrathoracic hemorrhage after placement of a subpleural catheter

, Daniel J. Boffa, MD; Frank C. Detterbeck, MD; Anthony W. Kim, MD November 07, 2011

An already uncommon postoperative complication affects two patients in unusual locations and via different mechanisms.
 

Can I be screened for ovarian cancer?

September 30, 2011

This information can help PAs and patients understand ovarian cancer and its symptoms and risk factors and to determine who should be screened.
 

Ovarian cancer: Breaking the silence

, September 16, 2011

More than 90% of women survive when ovarian cancer is caught early. The key is awareness, for both the patient and the PA.
 

What caused this mucosal diarrhea?

August 25, 2011

A patient presents to determine the cause of her abdominal cramping and the mucous and pink-red streaks in her stool.
 

Venous thromboembolism in cancer: What is the optimal treatment?

, August 04, 2011

Strong evidence favors use of low molecular weight heparin to treat and prevent VTE in patients with cancer, but many clinicians have yet to modify their clinical practice.
 

Laryngectomy: The silent unknowns and challenges of surgical treatment

August 01, 2011

Patients with laryngeal cancer who decide to have a total laryngectomy face a number of 
difficulties, including loss of speech and the consequent social isolation.
 

Lynch syndrome

July 29, 2011

Lynch syndrome, an autosomal dominant disorder that carries a high risk for colorectal and endometrial cancers, can be best detected by obtaining a family cancer history, screening colorectal and endometrial cancers for LS, and genetic testing of at-risk patients and family members.
 

Chronic lymphocytic leukemia: The most common leukemia in adults

May 03, 2011

Primary care PAs may not treat CLL, but they do need to understand its complications because most CLL patients eventually require therapy.
 

Esophageal carcinoma: Matching 
patients with treatment methods

, Richard T. Miller, MD January 18, 2011

Since cancer of the esophagus has a high morbidity and mortality, choosing the correct treatment method and knowing the facts are key.
 

Small bowel necrosis in association with jejunal tube feeding

Andrea N. Sarap, PA-C; Michael D. Sarap, MD, FACS; Jennifer Childers, PA-C November 15, 2010

Despite successful gastrojejunostomy reconstruction and jejunal feeding tube placement, this patient died from a rare complication.
 

Neuroblastoma: Management of a 
common childhood malignancy

November 01, 2010

An understanding of presentation, staging, and the genetic influence of this extracranial tumor can improve outcomes of affected children.
 

Thymoma: An uncommon cause of persistent anterior wall chest pain

, October 18, 2010

Previously diagnosed as costochondritis, chest pain that persisted despite treatment prompted a search for an alternate diagnosis.
 

BRCA gene testing in a woman with a family history of cancer

Terry D. Kober, PA-C; Miranda M. Collins, MEd, MPAS, PA-C August 16, 2010

The case of a woman at risk of breast cancer illustrates the importance of taking action; how a recent law protects all patients.
 

Rapidly growing abdominal tumor in a toddler

Holly L. Green, PA-C; Michael E. Rytting, MD; Charles S. Cox Jr, MD August 09, 2010

Worsening abdominal distention, intermittent vomiting, a palpable mass, and decreased activity signaled a life-threatening malignancy.
 

Cervical cancer: Updated screening guidelines

From CSAC, the Clinical and Scientific Affairs Council of the AAPA July 20, 2010

Key recommendations include age at initial screen, screening intervals, and discontinuation and the impact of the HPV vaccine.
 

Evolving purple lesions and nodules on the abdomen and forearm

July 19, 2010

An elderly man complains of plum-colored lesions, some of which had worsened and some of which had spontaneously regressed.
 

Helicobacter pylori infection: An update on diagnosis and management

July 06, 2010

Sequelae of infection are causative factors in gastric cancer. Eradication of the bacteria, however, can be difficult.
 

Worsening head pain and neurologic symptoms

May 24, 2010

The symptoms were concentrated in the patient's head and scalp, but the diagnosis involved a different and unexpected location.
 

Why won't this rash respond to treatment?

May 07, 2010

Despite numerous therapeutic attempts, the rash continued to spread, involving more and more of the patient's groin.
 

What's new in breast oncology

April 16, 2010

Genetic profiling with the 21-gene RT-PCR assay improves predictions for risk of 10-year recurrence and response to chemotherapy.
 

A rare presentation of metastatic breast cancer in a woman with apparent cholangiocarcinoma

Holly L. Johnson, MPAS, PA-C? March 08, 2010

Jaundice and intermittent abdominal pain were the only clues to a primary breast cancer that manifested without the usual symptoms.
 

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