Hematology

Persistent oral bleeding after toothbrushing

Lauren Neighbors, John L. Abt, DO, FACEP; Joyce Wagner, MCMS, PA-C May 16, 2012

A middle-aged woman experiences persistent gum bleeding after brushing her teeth, accompanied by foul breath.

Immune thrombocytopenic purpura develops in a 67-year-old female

Mackenzie L. Pennington, MS, PA-C, Alison C. Essary, MHPE, PA-C December 19, 2011

After a careful diagnostic workup and a process of elimination, the patient's attempt to treat her leg cramps was revealed to be the most probable cause of her hemorrhagic lesions.

Oral anticoagulation: A review of the current and emerging therapies

Mary C. McArthur, MS, MMS, PA-C, Elise K. Dzintars, MMS, PA-C; R. Brock Phillips, MMS, PA-C; Reamer L. Bushardt, PharmD, PA-C November 04, 2011

Now that options besides warfarin are available, clinicians must weigh the advantages and disadvantages, safety, tolerability, efficacy, price, and ease of use of each agent.

Profuse left-sided epistaxis and spiderlike lesions on a 66-year-old male

Jason C. Fowler, MPAS, PA-C, Peter F. White, MD, FRCS September 28, 2011

A man with a history of bleeding experiences has a number of strange lesions on the fingers, cheek, and tongue.

Immune (idiopathic) thrombocytopenic purpura in a 21-year-old student

Shaun Grammer, MS, PA-C, Leamor Kahanov, EdD, LAT, ATC September 12, 2011

Diagnosis of the adult form and the pediatric form of ITP may be based less on the calendar than on individual patient presentation.

Polycythemia rubra vera: An unlikely cause of severe pulmonary embolism

Rami N. Khouzam, MD, FACC, FACP, FASNC, Mary Jane Gallahan, PA-C, PhD? May 30, 2011

An elderly woman presented with mild pain in her leg and shortness of breath. The results of CT and laboratory testing led to the diagnosis of a rare myeloproliferative disorder.

Chronic lymphocytic leukemia: The most common leukemia in adults

Leslie Washburn, MPAS, PA-C May 03, 2011

Primary care PAs may not treat CLL, but they do need to understand its complications because most CLL patients eventually require therapy.

Abnormal protein deposition causes symptoms of dyspnea and fatigue

Eric Vickery, PA-C September 13, 2010

Light chain amyloid deposition can occur in any organ but the brain, disrupting the tissue architecture and interfering with organ function.

Lipid disorders

Leslie Kole, PA-C November 11, 2009

Hyperlipidemia is a major risk factor for coronary artery and heart diseases. This article reviews screening and the most effective approach to disease management in these patients.

Why was antiphospholipid antibody syndrome not included?

August 13, 2009

Genetic susceptibility to VTE: A primary care approach

Herbert D. Ridings, MA, PA-C; Lynn Holt; Rebecca Cook, MD; Marisa B. Marques, MD July 01, 2009

Patients with a genetic thrombophilia must be referred to a hematology specialist for long-term management.

Erythema infectiosum: Recognizing the many faces of fifth disease

Ellen D. Mandel, DMH, MPA, PA-C June 02, 2009

The multiple manifestations of this viral infection are described. Are you able to recognize these etiologies?

Multiple myeloma: Vague symptoms can challenge diagnostic skills

Eric Vickery, PA-C November 01, 2008

PAs should include this disease in the differential diagnosis for patients who present with nonspecific symptoms such as bone pain, fatigue, and recurrent infections.