Dosing of phenytoin is complicated by its unique properties: it is highly lipophilic, highly protein-bound, and undergoes capacity-limited pharmacokinetics at therapeutic levels.

IgE-mediated allergy to opioids is rare but life-threatening, so distinguishing between a true allergic reaction and side effects to a previously prescribed opioid is crucial.

Most extravasation injuries do not result in significant harm, but prompt recognition and early treatment are crucial.

Vancomycin should be dosed aggressively early on, with a loading dose given that is sufficient for rapid achievement of target concentrations.

This month's topics are how to initiate treatment in patients with hypothyroidism and cobalamin dosing in patients with pernicious anemia.

This month's topics are preventing myopathies when using simvastatin and safe use of amiodarone.

This month's topics are using erythromycin for GI motility, choosing a sunscreen, and DVT prophylaxis with enoxaparin in obese patients.

This month's topics are the new opioid analgesic tapentadol and using enoxaparin after prosthetic valve surgery.

Are generic products truly equivalent to their brand name counterparts, particularly narrow therapeutic index (NTI) medications such as antiepileptics, immunosuppressants, anticoagulants, and levothyroxine?

This month's questions are whether statins are best taken at night and whether OTC fish oil supplements are as effective as Lovaza.